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What are Prions?

Prions are the infectious agents responsible for several neurodegenerative diseases in mammals. This happens due to the abnormal folding of the proteins in the brain. It refers to the hypothesis that the infectious agents causing the diseases contain only proteins. It explained why infectious agents are resistant to ultraviolet radiation. They can break down the nucleic acids but are receptive to substances that denature proteins.

Structure of Prions

Prions are found all over the body but the ones that cause diseases are structurally different. Few of them are even resistant to proteases. The two isoforms of prions are:

Types of Prion Diseases

Prion diseases can be of three types- acquired, sporadic, or genetic.

Symptoms of Prion Disease

Prion disease has a long incubation period, often years. However, when symptoms develop, they worsen progressively and at times rapidly. Some of the common symptoms of this illness are:

Diagnosis of Prions Disease

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