What is Liver?

The liver is an essential organ that has many functions in the body, including making proteins and blood clotting factors, manufacturing triglycerides and cholesterol, glycogen synthesis, and bile production. It is a large organ that sits on the right-hand side of the belly.

Symptoms of Liver Disease:

  1. Jaundice
  2. Abdominal pain and swelling
  3. Confusion
  4. Bleeding
  5. Fatigue and weight loss.


Functions of Liver

  • Production of Bile: It produces bile, It helps in the digestion and absorption of fats, vitamins, and cholesterol is produced in that.
  • Absorption of Bilirubin: Bilirubin is formed by the breakdown of hemoglobin. The iron released is stored in the liver to make next-generation blood cells.
  • Supporting Blood Clots: Bile is responsible for the absorption of vitamin K. If bile is not produced, clotting factors will not be produced.
  • The metabolization of Fats: Bile helps in the breakdown and digestion of fats.
  • Carbohydrate Metabolization: The carbohydrates stored in the liver as glycogen are broken down into glucose and released into the blood to maintain glucose levels.
  • Storage of Vitamins and Minerals: It stored Vitamins A, D, E, K, and B12. It also stores iron in the form of ferritin to form new red blood cells.
  • The metabolization of Proteins: Bile helps in the digestion of proteins.
  • Filtering Blood: It filters hormones, alcohol, etc are filtered from the blood.
  • Immunological Function: It contains Kuffer cells involved in immune activity. These destroy any disease-causing agents.
  • Albumin Production: Albumin transports fatty acids and steroids to maintain correct pressure and prevent leakage of blood vessels.
  • Angiotensinogen Synthesis: This hormone is responsible for the narrowing of blood vessels which increases blood pressure.
  • Regeneration: It has the ability to regrow in all vertebrates. In humans, regeneration takes 8-15 days. In mice, the same process takes around 5-7 days.

Liver Diseases

  • Fascioliasis
  • Cirrhosis
  • Hepatitis
  • Fatty Liver Disease:
  • Liver Cancer: Alcohol and hepatitis are the major cause of liver cancer, It can be classified as Hepatocellular carcinoma and cholangiocarcinoma.

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